High Resolution Magic Angle Spinning (HR-MAS) NMR

Developed by: Centro Andaluz de Nanomedicina y Biotecnología BIONAND

Description

HR-MAS NMR is based on solid-state NMR, which uses magic-angle spinning at high speeds to average anisotropic interactions, leading to narrower widths. The moderate spin rates used in HR-MAS allows high resolution spectra to be obtained from intact tissue, i.e., without the need of any metabolite extraction procedure.


Equipment:

Bruker Avance 600 MHz NMR spectrometer + HR-MAS Probe

Applications

  • Metabolomics of intact tissue samples (tumor biopsies, …)
  • Structure Characterization and Elucidation of partially insoluble compounds)

Mª Carmen Muñoz

mcmunoz@bionand.es

952 367 637