Animal isolation device for experimental radiotherapy treatment
Developed by: Instituto de Investigación Sanitaria Hospital La Paz
Description and essential characteristics
The device (1) is made up of two boxes or isolation chambers (10,20), arranged one inside the other. Each box is provided with its respective closure lid (the closure lids being not coincident with each other), holes (13,22) for the entrance of experimental treatment probes, ventilation ports (14,23), and in addition means of fixation (16) for air filters intended to be located on the ventilation ports. The holes and ventilation ports of the outer chamber are coincidental with the holes and ventilation ports of the inner box, respectively.
The system also consists of the following:
- Plugs to be inserted in the holes and ventilation ports, thereby achieving air tight hermetic sealing of the device.
- Immobilization means (15), which are permanently or temporarily joined, adhered or fixed to the internal surface of the inner box so as to achieve the optimal animal adherence, thus avoiding animal movements inside the box.
The design of the device guarantees the perfect isolation of the animal, which is located within the inner chamber.
The system also includes external pouches arranged in one of its sides that allow the introduction of the user's hands for handling the animal under hygiene and isolation conditions.
The device could be manufactured with materials isodense with water, ideal for absorbed radiation dose calculations.
The different advantages provided by the device—animal fixation, immobilization and isolation, as well as conditions of safety and hygiene—make it feasible to use with either of the two main modalities of radiotherapy (external and brachytherapy).
Additionally, the device can be adapted to different sizes of animals, as well as varying levels of radiotherapy accuracy, including the higher ones corresponding to stereotactic systems.
The device can also be used in (human) clinical facilities, as it complies with the required conditions of isolation, safety and hygiene, and is non-polluting.
Isolation and immobilization animals for tests with high precision radiotherapy.
Estado de protección
Spanish patent P201031519, granted in April 2013.
International patent application PCT/ES2011/070709.
Innovation Support Unit
Foundation for Biomedical Research of La Paz University Hospital - FIBHULP-IdiPAZ
Edificio IdiPAZ, Planta Baja
Paseo de la Castellana, 261
Tfno: 91 207 12 34
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