Ghrelin -O -acyl transferase (GOAT) and their uses.
Presently, several biomarkers are used in clinical practice for the diagnosis of prostate cancer from non-invasive methods. Specifically, the most widely used is the PSA (prostate specific antigen), which has a sensitivity between 20 and 90 % depending on trim level and tumour grade.
In particular, it is to provide a diagnostic tool that serves as a clinically effective use of alternative PSA traditionally used and with a not very high cost. Researchers have found that by measuring expression levels of the GOAT (ghrelin -O -acyl transferase), can be used as a useful diagnostic tool in clinical practice, given its high specificity and sensitivity (66 % and 81 % respectively).
The use of biomarkers studied has the following advantages over the currently used methods for the diagnosis of prostate cancer:
- Minimally invasive methods.
- Good specificity and sensitivity.
- Moderate cost.
Estado de protección
This technology is protected by International Patent Application PCT.
The research group is looking for a partner interested in a license and/or a collaboration agreement to further develop and exploit this innovative technology.
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