Unidad de Analítica

Desarrollado por: Instituto de Investigación Sanitaria La Fe


The Analytical Unit (AU) offers analytical support in a wide variety of research projects related to the determination of relevant biomolecules with a molecular weight ranging from 50 to 1000 Da in biological matrices obtained from different sort of sources (e.g. cells, tissue, serum and other physiological fluids). Thereby, the AU arises as a potent platform to provide specialized services to internal and external customers, including enterprises focused on the pharmaceutical, cosmetic, nutraceutic and biotechnological sector, thus promoting the collaboration in R+D projects with both public and private entities.

The obtaining of the Good Laboratory Practices (GLP) certificate in 2009 ensures that all the offered services are conducted in compliance with rigorous quality standards.  Furthermore, the AU deals with an additional high value-added due to the clinical experience of La Fe Hospital, thus converging both expertise and cutting-edge equipment.



The AU is located in a more than 100 m2 facility, including segregated laboratory space designed for dealing with sample processing, analytical systems management and data analysis. Currently, the analytical platform of the UA involves the following state of the art instruments that combine both chromatography and mass spectrometry techniques: 

Liquid chromatographs coupled to triple quadrupole mass analysers

UPLC-MS (QqQ), Waters Acquity-Xevo TQ-S

UPLC-MS (QqQ), Agilent 1290-6460

HPLC-MS (QqQ), Waters 2795XL-Quattro Micro

Liquid chromatographs coupled to quadrupole-time of flight mass analysers

UPLC-MS (QToF), Waters Acquity-Synapt

HPLC-MS (QToF), Agilent 1100, ABSciex QSTAR Elite

Gas chromatograph coupled to quadrupole-time of flight mass analyser

GC-MS (QToF), Agilent 7890A-7200

Additionally, a liquid chromatography Agilent 2695 with UV-VIS (Agilent DAD 2996) or fluorescent detection (Shimadzu RF535) systems are also available.



Scientific Leadership:  Jose V. Castell, PhD 

Responsible Technician: Zacarías León, PhD

Dirección postal

e-mail: analytical_unit@iislafe.es

Phone: (+34) 608 897 313 (ext. 485635)