Metodo para entrega eficiente de moleculas terapeuticas a celulas CXCR4+
Desarrollado por: Instituto de Investigación Biomédica Sant Pau (IIB Sant Pau)
The invention relates to conjugates comprising a targeting moiety specific for the CXCR4 based on the polyphemusin-derived peptide and a therapeutic or imaging agent. The invention relates as well to the application of said conjugates for the therapy and diagnostics which require the specific targeting to CXCR4+cell. This technology provides for the first time a promising, highly targeted drug delivery system for the treatment of colorectal tumor cells.
Modular protein approaches to nanocarriers for pharmaceuticals permits a treatment with a precise adjustmen of the dosage regimen, allowing a considerably important reduction of side effects.
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