Sistema para evaluar el tejido miocárdico infartado por la medición de impedancia eléctrica

Desarrollado por: Instituto de Investigación Biomédica Sant Pau (IIB Sant Pau)


Ventricular arrhythmias are responsible of approximately 60% of sudden deaths in patients with a previously cardiac infarction. Postinfarction ventricular arrhythmias can be supressed by electrical catheter ablation of the arrhythmogenic substrate but this procedure requires a precise location of the target ablation sites scattered within the infarcted region (infarct scar). The cardiac navigation systems currently employed in the catheter ablation procedures utilize the mapping of low voltage endocardial electrograms although this technique cannot determine if the scar is completely transmural or not.

It has been reported that normal and infarcted myocardium cam be recognized by measuring the myocardial electrical impedance using an intracardiac electrocatheter. However, current systems can only measure the impedance at few selected frequencies during the cardiac cycle, thereby hindering its use.


The aim of the present invention is to provide a measuring device to assess the extent and deepness of myocardial infarcted tissue by using the novel technique of fast broadband electrical impedance spectroscopy. This new technique enables time-varying bioimpedance measurements within the entire cardiac cycle, at simultaneous multiple frequencies.

Estado de protección

PCT patent with application number PCT/EP2016/056933, filed on March 30, 2016.

Owned by Institut de Recerca Hospital de la Santa Creu i Sant Pau and Universitat Politècnica de Barcelona.

Cooperación que se desea

Technology out-licensing for development and commercialization.

Responsable: Miriam Ors

Contacto (Tel./mail): mors(ELIMINAR)    / 93 553 78 69

En busca de codesarrolladores, En desarrollo, Transferible
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